![]() For these reasons, the introduction of PBS was thought to largely mitigate the need for external apertures. From a technical standpoint, these advantages allow PBS to shape a dose distribution to closely match the target outline while minimizing the neutron production relative to its passive scattering counterpart. ![]() ![]() Pencil beam scanning offers 2 clinical advantages over passive scattering proton beam therapy: PBS can significantly spare healthy tissues proximal to the planning target volume (PTV) owing to its ability to create variable width spread-out Bragg peaks across the target and with the addition of computer-aided beamlet weight optimization, PBS gives rise to intensity-modulated proton beam therapy (IMPT), which is analogous to IMRT in external photon beam therapy. One of the most impactful developments since the advent of proton therapy has been pencil beam scanning (PBS), a treatment delivery modality where a narrow proton beam (beamlet) is steered within the treatment field by using a time-variant magnetic field. The field of proton therapy has grown rapidly since its initial proposal, fueled by the prospects of increased local tumor control and reduction of treatment toxicities in comparison to conventional photon-based treatment modalities. ![]()
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